Searchable abstracts of presentations at key conferences in endocrinology

ea0031p183 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2013

The effects of Syzygium aromaticum-derived oleanolic acid on reactive oxygen species in the heart, liver and kidney of STZ-induced diabetic rats

Mkhwanazi Blessing , Sibiya Ntethelelo , Serumala Metse , Myburg Rene , Musabayane Cephas T

The onset of diabetic complications is attributed to sustained hyperglycemia which triggers the generation of free radicals and oxidative-related damage in the retina, renal glomerulus and peripheral nerves. Recent studies report that intense glycaemic control by the subcutaneous administration of insulin cannot completely restore the balance between reactive oxygen species and antioxidants. Preliminary studies in our laboratory indicate that transdermally delivered Syzygi...